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Optics

Our Technology

Fourier Ptychography Microscopy (FPM) is a computational imaging technique that
reconstructs high-resolution images by utilizing three-dimensional information of the base image.
SMALLMACHINES possesses the world's first advanced FPM-based optical technology for bioapplications that does not require fluorescent staining.

Comparative Advantages to Existing Solutions

Limitations of Conventional Microscopes

  • Trade-off between field of view (FoV), depth of field (DoF), and resolution
  • Increased maintenance costs, imaging frequency, and analysis time due to the use of high-magnification lenses

Improvement Methods

  • High-Resolution Image Reconstruction using the FPM Algorithm
    - Maximization of Low-Magnification Optical System Efficiency
  • Reduction in maintenance costs, shortened analysis time, and improved accuracy through the use of low-magnification lenses
  • Multi-light source measurement system - transmissive 3D design - LED light source optimization
  • 3D shape reconstruction

FPM algorithm

FPM algorithm

Improved efficiency of low-magnification optical system

Multi-light source measurement system

Multi-light source measurement system

3D shape reconstruction

3D shape reconstruction

Ensuring data reliability

  • FoV : The visible area captured by an imaging system
  • DoF : The range of sharp focus in an image